What is an abortive transduction?

What is an abortive transduction? This an event in which the transducing DNA fails to be inputted or incorporated into the receiving chromosome

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abortive transduction

Abortive transduction is the process of introducing a linear fragment of DNA from one bacterial cell into another using a bacteriophage vector. The size of the DNA fragment is determined by how much DNA the bacteriophage will package into a phage capsid, which is about 44. kb for phage P22 and 90. kb for phage P1. in abortive transduction, The DNA fragment does not recombine into the chromosome nor does it replicate when the recipient cell replicates its chromosome. Thus, only one daughter cell inherits the abortive DNA you can also check out meiosis division process here. fragment. The genes encoded on the abortive DNA fragment are expressed in the recipient cell and can be used to perform complementation experiments. read more here


abortive transduction happens through either the lytic cycle or the lysogenic cycle. When bacteriophages (viruses that infect bacteria) that are lytic infect bacterial cells, they harness the replicational, transcriptional, and translation machinery of the host bacterial cell to make new viral particles (virions).

The new phage particles in abortive transduction are then released by lysis of the host.

In the lysogenic cycle, the phage chromosome is integrated as a prophage into the bacterial chromosome, where it can stay dormant for extended periods of time.

According to wikipedia, in their article on abortive transduction, “If the prophage is induced (by UV light for example), the phage genome is excised from the bacterial chromosome and initiates the lytic cycle, which culminates in lysis of the cell and the release of phage particles. Generalized transduction (see below) occurs in both cycles during the lytic stage, while specialized transduction (see below) occurs when a prophage is excised in the lysogenic cycle.”