Reproduction in amoeba How does amoeba reproduce? Is there a special reproductive system found in amoeba? First of all amoeba is a microscopic animal. Talking about amoeba as a microscopic organisms or animal we simply mean that this animal called amoeba cannot be seen with the naked eye except with the aid of a microscope How reproduction occur in amoeba as an organism Reproduction in amoeba occurs through a process called binary fission. 1. What is binary fission Binary fission is a process of asexual reproduction in unicellular organisms in which a single cell divides into two equal parts by mitosis to produce two new daughter cells. 2. What is multiple fission? Multiple fission is a reproductive process in amoeba to which Division of the cell is divided into more than two. .