THE SKIN AND IT’S FUNCTIONS

the skin and it’s functions. SKIN. Structure of skin:; The skin of farm animals (Fig. 29.12) has been described as the largest organ of the body. It covers the outer surfaces of all animals. The skin is made up of two layers – epidermis and dermis.

Epidermis part of the skin

The epidermis is the outermost layer and it is made up of three layers: (i) cornified layer (ii) granular layer (iii) malpighian layer.

The cornify layer of the skin:

It is the outermost layer of the epidermis. It is made up of flat, hard and scaly cells. The cells of cornified layer are dead.

The granular layer of the skin:

This contains the living cells where active division of cells takes place. These cells replace the cells of the granular layer which in turn are replacing the cells of the cornified layer which are constantly being worn-out.

(iii)

The Malpighian layer of the skin:

This contains granules of pigment called melanin. This hair pigment is responsible for skin colour. The melanin also prevents the penetration of a lot of violet rays of sunlight.

The Malpighian layer also contains another pigment called keratin which is responsible for the toughness and flexibility of the skin.

Dermis:fibrous collective tissues. The dermis contains nerves which enable the skin to be sensitive to changes in its environment such as pain, heat, temperature, touch, cold, etc.. The blood and lymph vessels supply materials to the skin, remove wastes from the skin cells, and carry out temperature regulation. The sweat glands which consist of a coiled tubular gland opening into the epidermis excrete water and salts as sweat, sebaceous or oil gland which produces an oily substance called sebum. This helps to lubricate the hair and make it waterproof, while the erector muscle controls the erection of the hairs on the skin surface by its contraction and relaxation. Underneath the skin is a layer of fat called subcutaneous fatty tissue. This fat layer varies in thickness, depending on the part of the body.

FUNCTIONS OF THE SKIN

The functions of the skin include the following:
(1) Protection: The skin protects the inner skin or tissue from mechanical injuries, bacterial infection, and ultraviolet rays of the sunlight and against desiccation.

(2) Excretion: The skin excretes excess water, mineral salts and nitrogenous wastes through the sweat glands as sweat
(3) Sensitivity: The skin is sensitive to its environment through the specialized sensory nerve endings scattered in the dermis. The skin is sensitive to such stimuli as change in temperature, pressure, pain and cold.
(4) Production of vitamin D: The skin manufactures Vitamin D by using infra-red rays from sunlight
(5) Production of milk in females: The mammary gland which is a modification of the skin produces milk which is used for feeding the young one.
(6) Storage of preserved foods: Fats are stored under the dermis of mammals, especially those of pigs. Fats also from an insulating layer.

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(7) Regulation of body temperature: when an animal is hot, blood vessels under the epidermis of the skin dilate (vasodilation) and more blood is brought to the surface to be cooled through the process of convection and radiation. On the other hand, the blood vessels of the skin constrict (vasoconstriction) in cold weather, thereby conserving heat.

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Facts about the skin

The skin is the body’s largest organ, covering the entire body. In addition to serving as a protective shield against heat, light, injury, and infection, the skin also:

Regulates body temperature

Stores water and fat

Is a sensory organ

Prevents water loss

Prevents entry of bacteria

Throughout the body, the skin’s characteristics vary (for example, thickness, color, and texture). For instance, the head contains more hair follicles than anywhere else, while the soles of the feet contain none. In addition, the soles of the feet and the palms of the hands are much thicker than skin on other areas of the body.

The skin is made up of the following layers, with each layer performing specific functions:

Epidermis

Dermis

Subcutaneous fat layer

Epidermis

The human skin is the outer covering of the body and is the largest organ of the integumentary system. The skin has up to seven layers of ectodermal tissue and guards the underlying muscles, bones, ligaments and internal organs.[1] Human skin is similar to most of the other mammals skin, and human skin is very similar to pig skin.[2][3] Though nearly all human skin is covered with hair follicles, it can appear hairless. There are two general types of skin, hairy and glabrous skin (hairless).[4] The adjective cutaneous literally means “of the skin” (from Latin cutis, skin).

Because it interfaces with the environment, skin plays an important immunity role in protecting the body against pathogens[5] and excessive water loss.[6] Its other functions are insulation, temperature regulation, sensation, synthesis of vitamin D, and the protection of vitamin B folates. Severely damaged skin will try to heal by forming scar tissue. This is often discolored and depigmented.

In humans, skin pigmentation varies among populations, and skin type can range from dry to oily. Such skin variety provides a rich and diverse habitat for bacteria that number roughly 1000 species from 19 phyla, present on the human skin.

The epidermis is the thin outer layer of the skin that consists of three types of cells:

Squamous cells. The outermost layer is continuously shed.

Basal cells. Basal cells are found just under the squamous cells.

Melanocytes. Melanocytes are found in every layer of the epidermis and make melanin, which gives the skin its color.

Dermis

The dermis is the middle layer of the skin. The dermis contains the following:

Blood vessels

Lymph vessels

Hair follicles

Sweat glands

Collagen bundles

Fibroblasts

Nerves

The dermis is held together by a protein called collagen, which is made by fibroblasts. This layer gives skin flexibility and strength. It also contains pain and touch receptors.

Subcutaneous fat layer

The subcutaneous fat layer is the deepest layer of skin and consists of a network of collagen and fat cells. It helps conserve the body’s heat and protects the body from injury by acting as a shock absorber.

Structure of the skin

Skin has mesodermal cells, pigmentation, such as melanin provided by melanocytes, which absorb some of the potentially dangerous ultraviolet radiation (UV) in sunlight.

It also contains DNA repair enzymes that help reverse UV damage, such that people lacking the genes for these enzymes suffer high rates of skin cancer.

One form predominantly produced by UV light, malignant melanoma, is particularly invasive, causing it to spread quickly, and can often be deadly. Human skin pigmentation varies among populations in a striking manner. This has led to the classification of people(s) on the basis of skin color.

In terms of surface area, the skin is the second largest organ in the human body (the inside of the small intestine is 15 to 20 times larger). For the average adult human, the skin has a surface area of between 1.5-2.0 square meters (16.1-21.5 sq ft.). The thickness of the skin varies considerably over all parts of the body, and between men and women and the young and the old. An example is the skin on the forearm which is on average 1.3 mm in the male and 1.26 mm in the female.

The average square inch (6.5 cm²) of skin holds 650 sweat glands, 20 blood vessels, 60,000 melanocytes, and more than 1,000 nerve endings.[11][better source needed] The average human skin cell is about 30 micrometers in diameter, but there are variants. A skin cell usually ranges from 25-40 micrometers (squared), depending on a variety of factors.

Skin is composed of three primary layers: the epidermis, the dermis and the hypodermis.[10]
Layers, Receptors, and Appendages of Human Skin
Epidermis

Epidermis

Epidermis, “epi” coming from the Greek meaning “over” or “upon”, is the outermost layer of the skin. It forms the waterproof, protective wrap over the body’s surface which also serves as a barrier to infection and is made up of stratified squamous epithelium with an underlying basal lamina.

The epidermis contains no blood vessels, and cells in the deepest layers are nourished almost exclusively by diffused oxygen from the surrounding air[12] and to a far lesser degree by blood capillaries extending to the outer layers of the dermis. The main type of cells which make up the epidermis are Merkel cells, keratinocytes, with melanocytes and Langerhans cells also present. The epidermis can be further subdivided into the following strata (beginning with the outermost layer): corneum, lucidum (only in palms of hands and bottoms of feet), granulosum, spinosum, basale. Cells are formed through mitosis at the basale layer. The daughter cells (see cell division) move up the strata changing shape and composition as they die due to isolation from their blood source. The cytoplasm is released and the protein keratin is inserted. They eventually reach the corneum and slough off (desquamation).

This process is called “keratinization”. This keratinized layer of skin is responsible for keeping water in the body and keeping other harmful chemicals and pathogens out, making skin a natural barrier to infection.

2D projection of a 3D OCT-tomogram of the skin at the fingertip, depicting the stratum corneum (~500 µm thick) with the stratum disjunctum on top and the stratum lucidum in the middle. At the bottom are the superficial parts of the dermis. The sweatducts are clearly visible. (See also: Rotating 3D Version)
Components

The epidermis contains no blood vessels, and is nourished by diffusion from the dermis. The main type of cells which make up the epidermis are keratinocytes, melanocytes, Langerhans cells and Merkel cells. The epidermis helps the skin to regulate body temperature.

Layers

Epidermis is divided into several layers where cells are formed through mitosis at the innermost layers. They move up the strata changing shape and composition as they differentiate and become filled with keratin. They eventually reach the top layer called stratum corneum and are sloughed off, or desquamated. This process is called keratinization and takes place within weeks. The outermost layer of the epidermis consists of 25 to 30 layers of dead cells.
Sublayers

Epidermis is divided into the following 5 sublayers or strata:

Stratum corneum
Stratum lucidum
Stratum granulosum
Stratum spinosum
Stratum germinativum (also called “stratum basale”).

Blood capillaries are found beneath the epidermis, and are linked to an arteriole and a venule. Arterial shunt vessels may bypass the network in ears, the nose and fingertips.

Genes and proteins expressed in the epidermis

About 70% of all human protein-coding genes are expressed in the skin.[13][14] Almost 500 genes have an elevated pattern of expression in the skin. There are less than 100 genes that are specific for the skin and these are expressed in the epidermis.[15] An analysis of the corresponding proteins show that these are mainly expressed in keratinocytes and have functions related to squamous differentiation and cornification.

Dermis

The dermis is the layer of skin beneath the epidermis that consists of connective tissue and cushions the body from stress and strain. The dermis is tightly connected to the epidermis by a basement membrane. It also harbors many nerve endings that provide the sense of touch and heat. It contains the hair follicles, sweat glands, sebaceous glands, apocrine glands, lymphatic vessels and blood vessels. The blood vessels in the dermis provide nourishment and waste removal from its own cells as well as from the Stratum basale of the epidermis.

The dermis is structurally divided into two areas: a superficial area adjacent to the epidermis, called the papillary region, and a deep thicker area known as the reticular region.
Papillary region

The papillary region is composed of loose areolar connective tissue. It is named for its fingerlike projections called papillae, that extend toward the epidermis. The papillae provide the dermis with a “bumpy” surface that interdigitates with the epidermis, strengthening the connection between the two layers of skin.

In the palms, fingers, soles, and toes, the influence of the papillae projecting into the epidermis forms contours in the skin’s surface. These epidermal ridges occur in patterns (see: fingerprint) that are genetically and epigenetically determined and are therefore unique to the individual, making it possible to use fingerprints or footprints as a means of identification.
Reticular region

The reticular region lies deep in the papillary region and is usually much thicker. It is composed of dense irregular connective tissue, and receives its name from the dense concentration of collagenous, elastic, and reticular fibers that weave throughout it. These protein fibers give the dermis its properties of strength, extensibility, and elasticity.

Also located within the reticular region are the roots of the hairs, sebaceous glands, sweat glands, receptors, nails, and blood vessels.

Tattoo ink is held in the dermis. Stretch marks often from pregnancy and obesity, are also located in the dermis.
Subcutaneous tissue
The subcutaneous tissue (also hypodermis and subcutis) is not part of the skin, and lies below the dermis of the cutis. Its purpose is to attach the skin to underlying bone and muscle as well as supplying it with blood vessels and nerves. It consists of loose connective tissue, adipose tissue and elastin. The main cell types are fibroblasts, macrophages and adipocytes (subcutaneous tissue contains 50% of body fat). Fat serves as padding and insulation for the body.

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    WEED AND THEIR BOTANICAL NAMES
    1. ENVIRONMENTAL FACTORS AFFECTING AGRICULTURAL PRODUCTION
    2. DISEASES
    3. 52. SOIL MICRO-ORGANISMS
    4. ORGANIC MANURING
    5. FARM YARD MANURE
    6. HUMUGRAZING AND OVER GRAZING
    10. IRRIGATION AND DRAINAGES

    7. COMPOST
    8. CROP ROTATION
    9.
    11. IRRIGATION SYSTEMS
    12. ORGANIC MANURING
    13. FARM YARD MANURE
    14. HUMUS
    15. COMPOST
    16. CROP ROTATION

    IRRIGATION AND DRAINAGE
    19. IRRIGATION SYSTEMS
    20. INCUBATORS
    21. MILKING MACHINE
    22. SIMPLE FARM TOOLS
    23. AGRICULTURAL MECHANIZATION
    24. THE CONCEPT OF MECHANIZATION
    25. PROBLEMS OF MECHANIZATION

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